Photo. Portrait of Holger Fröhlich.

Prof. Dr.
Holger Fröhlich

Associated Principal Investigator Life Sciences & Health

Prof. Dr. Holger Fröhlich holds a diploma (focus area: Artificial Intelligence) and PhD in Computer Science. After positions as a postdoc at the German Cancer Research Center and as a Senior Scientist at Cellzome AG (now an enterprise of Glaxo-Smith-Kline), he was appointed an associate professorship at the University of Bonn in 2010. In 2015 he joined the global biopharmaceutical company UCB and became the Director of an AI and Data Science research team. Since 12/2019 HF is Head of the AI & Data Science group and Deputy Head of the Department of Bioinformatics at the Fraunhofer Institute for Algorithms and Scientific Computing in Sankt Augustin. In addition, he is teaching as an honorary Professor in the Master programs Life Science Informatics and Computer Science at the University of Bonn.


Holger Fröhlich’s focus is on the development and application of data science (specifically AI/ML) methods in biomedicine, with focus on early drug discovery, precision medicine and clinical trials. In this context, Holger Fröhlich has developed over the last 20 years a broad spectrum of data science approaches, including techniques for multi-modal data integration, (generative) time series modeling, hybrid AI approaches (ODE/NN combinations, Graph Neural Networks) and causal machine learning. He is author and co-author of more than 180 scientific publications. He has been coordinator of three EU projects (JNPD ADIS, ERA PerMed DIGIPD, Marie-Sklodowska-Curie doctoral network AIPD), and partner in multiple further national and international research consortia as well as industry collaborations. Furthermore, he is scientific advisory board member of the international AI graduate school HIDSS4Health of the Helmholtz society.