Prof. Dr.
Holger Fröhlich
Principal Investigator
Life Sciences & Health
Prof. Dr. Holger Fröhlich holds a Diploma (with a specialization in Artificial Intelligence) and a PhD in Computer Science. After postdoctoral research at the German Cancer Research Center and a subsequent position as Senior Scientist at Cellzome AG (now part of GlaxoSmithKline), he was appointed Associate Professor at the University of Bonn in 2010.
In 2015, he joined the global biopharmaceutical company UCB, where he became Director of an AI and Data Science research team. From December 2019 to December 2025, he served as Head of the AI & Data Science Group and Deputy Head of the Department of Bioinformatics at the Fraunhofer Institute for Algorithms and Scientific Computing (SCAI) in Sankt Augustin. Since January 2026, he has been Head of the Department of Biomedical AI & Data Science at the same institute.
In parallel, he teaches as a professor in the Master’s programs Life Science Informatics and Computer Science at the University of Bonn. Since October 2025, he has also been affiliated as a Full Professor with the Institute for Digital Medicine at the University Hospital Bonn.
Holger Fröhlich’s focus is on the development and application of data science (specifically AI/ML) methods in biomedicine, with focus on early drug discovery, precision medicine and clinical trials. In this context, Holger Fröhlich has developed over the last 20 years a broad spectrum of data science approaches, including techniques for multi-modal data integration, (generative) time series modeling, hybrid AI approaches (ODE/NN combinations, Graph Neural Networks) and causal machine learning. He is author and co-author of more than 180 scientific publications. He has been coordinator of three EU projects (JNPD ADIS, ERA PerMed DIGIPD, Marie-Sklodowska-Curie doctoral network AIPD), and partner in multiple further national and international research consortia as well as industry collaborations. Furthermore, he is scientific advisory board member of the international AI graduate school HIDSS4Health of the Helmholtz society.