{"id":43808,"date":"2026-11-13T10:59:33","date_gmt":"2026-11-13T10:59:33","guid":{"rendered":"https:\/\/lamarr-institute.org\/publication\/next-generation-sequencing-in-translational-sarcoma-research-biological-insights-and-emerging-directions\/"},"modified":"2026-11-13T10:59:33","modified_gmt":"2026-11-13T10:59:33","slug":"next-generation-sequencing-in-translational-sarcoma-research-biological-insights-and-emerging-directions","status":"publish","type":"publication","link":"https:\/\/lamarr-institute.org\/de\/publication\/next-generation-sequencing-in-translational-sarcoma-research-biological-insights-and-emerging-directions\/","title":{"rendered":"Next-Generation Sequencing in Translational Sarcoma Research: Biological Insights and Emerging Directions"},"content":{"rendered":"<p>Sarcomas are rare and heterogeneous malignancies for which molecular diagnostics increasingly complement histopathology, immunohistochemistry, FISH, and RT-PCR. This review summarizes the main research applications of next-generation sequencing (NGS) in sarcoma, with particular attention to mutation and variant discovery, fusion detection, biomarker development, assay validation, multi-omics integration, and the boundaries between exploratory research and clinical implementation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sarcomas are rare and heterogeneous malignancies for which molecular diagnostics increasingly complement histopathology, immunohistochemistry, FISH, and RT-PCR. This review summarizes the main research applications of next-generation sequencing (NGS) in sarcoma, with particular attention to mutation and variant discovery, fusion detection, biomarker development, assay validation, multi-omics integration, and the boundaries between exploratory research and clinical implementation.<\/p>\n","protected":false},"author":14,"featured_media":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"publication-type":[30],"publication-year":[1680],"class_list":["post-43808","publication","type-publication","status-publish","hentry","publication-type-article","publication-year-1680"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/publication\/43808","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/publication"}],"about":[{"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/types\/publication"}],"author":[{"embeddable":true,"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/users\/14"}],"version-history":[{"count":0,"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/publication\/43808\/revisions"}],"wp:attachment":[{"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/media?parent=43808"}],"wp:term":[{"taxonomy":"publication-type","embeddable":true,"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/publication-type?post=43808"},{"taxonomy":"publication-year","embeddable":true,"href":"https:\/\/lamarr-institute.org\/de\/wp-json\/wp\/v2\/publication-year?post=43808"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}